Streptavidin and Neutravidin Surfaces

for non-covalent oriented coupling of Biotin-modified biochemical species

Streptavidin and Neutravidin are tetrameric proteins that can bind four Biotin molecules (vitamin B7) or any other Biotin-conjugated species with a very high specificity. The Streptavidin/Neutravidin-Biotin bond is one of the strongest, non-covalent bonds known in biochemistry, having a dissociation constant of K_D = 10^-15 mol/L. Thus, it is often applied in bioanalytical applications.

PolyAn’s Streptavidin and Neutravidin matrices are covalently attached to the well surface, so that the molecules are less susceptible to desorption in the presence of surfactants, solutions of high ionic strength, or at high temperatures, compared to adsorptive immobilization.