Streptavidin and Neutravidin surfaces

PolyAn´s streptavidin or neutravidin functionalized microparticles are suitable for coupling biotin-modified biomolecules, e.g. oligonucleotides, peptides, proteins etc..

PolyAn offers to functionalize the surface with Avidin, Streptavidin and Neutravidin, respectively. The table below illustrates the differences between the variants (data of molecules in solution, not immobilized on bead surface):

 

  Avidin Streptavidin Neutravidin
Molecular Weight

67 kDa

53 kDa

60 kDa

Biotin-binding Sites

4

4

4

Isoelectric Point (pl)

10

6.8–7.5

6.3

Specificity

Low

High

Highest

Affinity for Biotin (Kd)

10-15 M

10-15 M

10-15 M

Nonspecific Binding

High

Low

Lowest

 

PolyAn can functionalize all the beads from our portfolio with the Streptavidin Avidin and Neutravidin surfaces, respectively:

Please do not hesitate to contact us (mail@poly-an.de), if you have any questions regarding our products. We are looking forward to your inquiry.