DNA combing (also called molecular combing) is a biochemical technique to produce an array of uniformly oriented and stretched DNA. The uniform orientation and stretching of the combed DNA is beneficial for nucleic acid hybridization studies such as fluorescence in situ hybridization (FISH), as it increases the accessibility for the hybridization target sequences as well as the resolution for the optical detection.
PolyAn's Combing Coverslips are surface-functionalized glass coverslips with standard dimensions of 22 x 22 mm and a standard thickness of 170 µm (Type #1.5) that are suitable for DNA combing. The Combing Coverslips are designed to allow fixation and stretching of DNA strands with low fluorescence background and improved signal-to-noise ratio for DNA detection. PolyAn's Combing Coverslips are compatible with the Genomic Vision combing systems FiberComb® and FiberVision®S. Other thicknesses and sizes are available upon request.
Contact
Fridtjof Lechhart,
COO/CFO PolyAn GmbH
PolyAn GmbH
Schkopauer Ring 6
12681 Berlin
Tel: +49 (0)30 912 078 0
Fax: +49 (0)30 912 078 11
Email: mail@poly-an.de
About PolyAn
PolyAn is a nanotechnology company specialized in the modification of surfaces using Molecular Surface Engineering (MSE). Since 1996 PolyAn develops and manufactures consumables for LifeScience applications that require high signal-to-noise ratios. Our products include supports for microarrays, fluorescence-encoded microparticles, and calibration tools for fluorescence imaging systems.