Solvent stable plates for covalent binding
Addressing a growing number of enquiries for reactive plates that are chemically robust, we have developed a range of reactive Polypropylene (PP) 96-well plates together with our customers. Our PP plates are designed for use in compound libraries in drug screening as well as synthesis and covalent immobilization of (bio-)molecules.
- High chemical compatibility, e.g. against solvents like DMSO, DMF, methanol, acetone ...
- Reactive polypropylene surfaces for synthesis and covalent immobilization
- Minimal leaching due to covalent immobilization
- Minimal unspecific binding due to 3D functional matrix
- Directed (bio-orthogonal) immobilization via click-chemistry with 3D-Azide surface
3D-Amino 96-well PP plate, F-bottom
00 800 001
Primary amines for covalent immobilization of compounds containing carboxyl, aldehyde or thiol groups as well as homoheterobifunctional linkers, e.g. N-Hydroxysuccinimide (NHS) or Succinimidyl 4-(N-maleidomethyl) cyclohexane-1-carboxylate (SMCC).
3D-Epoxy 96-well PP plate, F-bottom
00 800 251
Uncharged 3D-Epoxy matrix for reaction with nucleophilic groups, e.g. amines, thiols and hydroxyl groups, under formation of a covalent bond.
3D-NHS 96-well PP plate, F-bottom
00 800 451
Highly reactive surface for fast coupling of primary amine containing probes, e.g. proteins, glycans or other ligands.
3D-Azide 96-well PP plate, F-bottom
00 800 601
Surface for bio-orthogonal binding of oligonucleotides, peptides and small molecules (containing alkyne, cyclo-alkyne like DBCO groups) via click-chemistry.
PolyAn offers plates for colorimetric, chemiluminescence and fluorescent detection systems, respectively. Please go to these sections for ELISA-plates , covalently coated Streptavidin & Neutravidin plates or glass bottom plates with a wide range of surfaces and well designs.
Customized plate surfaces
Please do not hesitate to contact us, if you require a special surface for binding of your biomolecules that is not listed in the products table. Other plate formats and substrates can be equipped with our surfaces as part of our Molecular Surface Engineering Services. We are also happy to support you in developing suitable protocols for coating on our plates.