for non-covalent oriented coupling of Biotin-modified biochemical species

Streptavidin and Neutravidin are tetrameric proteins that can bind four Biotin molecules or Biotin-conjugated species with a very high specificity. The Streptavidin/Neutravidin-Biotin bond is the strongest non-covalent bond known in biochemistry (dissociation constant K_D = 10^-15 mol/L) and is often applied in bioanalytical applications.

PolyAn’s Streptavidin and Neutravidin is covalently attached to the well surface, making it less susceptible to desorption in the presence of surfactants, solutions of high ionic strength, or at high temperatures, compared to adsorptive immobilization.